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Exenatide CAS 141732-76-5

Exenatide CAS 141732-76-5

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Identification
Properties
Safety Data
Specifications & Other Information
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Identification

CAS Number

141732-76-5

Name

Exenatide

Sequence

His-Gly-Gly-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2

Synonyms

Exenatide [USAN]
L-histidylglycyl-L-glutamylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-aspartyl-L-leucyl-L-seryl-L-lysyl-L-glutaminyl-L-methionyl-L-glutamyl-L-glutamyl-L-glutamyl-L-alanyl-L-valyl-L-arginyl-L-leucyl-L-phenylalanyl-L-isoleucyl-L-glutamyl-L-tryptophyl-L-leucyl-L-lysyl-L-asparaginylglycylglycyl-L-prolyl-L-seryl-L-serylglycyl-L-alanyl-L-prolyl-L-prolyl-L-prolyl-L-serinamide
[141758-74-9]
141758-74-9 [RN]
Exenatide | AC 2993 |
exendin-4
VT9545000

SMILES

[H]/N=C(\N)/NCCC[[email protected]@H](C(=O)N[[email protected]@H](CC(C)C)C(=O)N[[email protected]@H](Cc1ccccc1)C(=O)N[[email protected]@H]([[email protected]@H](C)CC)C(=O)N[[email protected]@H](CCC(=O)O)C(=O)N[[email protected]@H](Cc2c[nH]c3c2cccc3)C(=O)N[[email protected]@H](CC(C)C)C(=O)N[[email protected]@H](CCCCN)C(=O)N[[email protected]@H](CC(=O)N)C(=O)NCC(=O)NCC(=O)N4CCC[[email protected]]4C(=O)N[[email protected]@H](CO)C(=O)N[[email protected]@H](CO)C(=O)NCC(=O)N[[email protected]@H](C)C(=O)N5CCC[[email protected]]5C(=O)N6CCC[[email protected]]6C(=O)N7CCC[[email protected]]7C(=O)N[[email protected]@H](CO)C(=O)N)NC(=O)[[email protected]](C(C)C)NC(=O)[[email protected]](C)NC(=O)[[email protected]](CCC(=O)O)NC(=O)[[email protected]](CCC(=O)O)NC(=O)[[email protected]](CCC(=O)O)NC(=O)[[email protected]](CCSC)NC(=O)[[email protected]](CCC(=O)N)NC(=O)[[email protected]](CCCCN)NC(=O)[[email protected]](CO)NC(=O)[[email protected]](CC(C)C)NC(=O)[[email protected]](CC(=O)O)NC(=O)[[email protected]](CO)NC(=O)[[email protected]]([[email protected]@H](C)O)NC(=O)[[email protected]](Cc8ccccc8)NC(=O)[[email protected]]([[email protected]@H](C)O)NC(=O)CNC(=O)[[email protected]](CCC(=O)O)NC(=O)CNC(=O)[[email protected]](Cc9cnc[nH]9)N

StdInChI

InChI=1S/C184H282N50O60S/c1-16-94(10)147(178(289)213-114(52-58-144(257)258)163(274)218-121(73-101-77-195-105-39-24-23-38-103(101)105)168(279)215-116(68-90(2)3)165(276)205-107(41-26-28-61-186)158(269)219-122(75-134(189)243)154(265)198-79-135(244)196-83-139(248)231-63-30-43-129(231)175(286)225-127(87-238)174(285)223-125(85-236)155(266)200-80-136(245)202-96(12)181(292)233-65-32-45-131(233)183(294)234-66-33-46-132(234)182(293)232-64-31-44-130(232)176(287)222-124(84-235)150(190)261)229-170(281)119(71-99-34-19-17-20-35-99)217-166(277)117(69-91(4)5)214-159(270)108(42-29-62-194-184(191)192)212-177(288)146(93(8)9)228-151(262)95(11)203-156(267)111(49-55-141(251)252)208-161(272)112(50-56-142(253)254)209-162(273)113(51-57-143(255)256)210-164(275)115(59-67-295-15)211-160(271)110(47-53-133(188)242)207-157(268)106(40-25-27-60-185)206-172(283)126(86-237)224-167(278)118(70-92(6)7)216-169(280)123(76-145(259)260)220-173(284)128(88-239)226-180(291)149(98(14)241)230-171(282)120(72-100-36-21-18-22-37-100)221-179(290)148(97(13)240)227-138(247)82-199-153(264)109(48-54-140(249)250)204-137(246)81-197-152(263)104(187)74-102-78-193-89-201-102/h17-24,34-39,77-78,89-98,104,106-132,146-149,195,235-241H,16,25-33,40-76,79-88,185-187H2,1-15H3,(H2,188,242)(H2,189,243)(H2,190,261)(H,193,201)(H,196,244)(H,197,263)(H,198,265)(H,199,264)(H,200,266)(H,202,245)(H,203,267)(H,204,246)(H,205,276)(H,206,283)(H,207,268)(H,208,272)(H,209,273)(H,210,275)(H,211,271)(H,212,288)(H,213,289)(H,214,270)(H,215,279)(H,216,280)(H,217,277)(H,218,274)(H,219,269)(H,220,284)(H,221,290)(H,222,287)(H,223,285)(H,224,278)(H,225,286)(H,226,291)(H,227,247)(H,228,262)(H,229,281)(H,230,282)(H,249,250)(H,251,252)(H,253,254)(H,255,256)(H,257,258)(H,259,260)(H4,191,192,194)/t94-,95-,96-,97+,98+,104-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,116-,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,146-,147-,148-,149-/m0/s1

StdInChIKey

HTQBXNHDCUEHJF-XWLPCZSASA-N

Molecular Formula

C184H282N50O60S.C2H4O2

Molecular Weight

4262.67

Properties

Appearance

White or off-white powder

Specifications and Other Information of Our Exenatide CAS 141732-76-5

Standard

Enterprise standard

Identification Methods

HPLC

Purity

95%min

Specific Optical Rotation

-45~-65°

Acetate content

<15%

Peptide purity

≥97.5%

TFA content

≤0.25%

Water

≤10%

Single Impurity

≤1.0%

Total Impurities

≤2.5%

Peptide content

≥80.0%%

Assay

95~105%

Storage

Store at 2-8 degrees

Application

Used as the pharmaceutical API,the main pancreatic cells to glucose-dependent insulin secretion, inhibit excessive secretion of glucagon and can delay gastric emptying.

Links

This product is sold exclusively through our sales company Watson International Ltd, and please click the link below for details.
http://www.watson-int.com/exenatide-cas-141732-76-5/